The most demanding challenge for cyber security in the digital transformation of enterprises, public institutions and citizens is nowadays represented by the  integration of different systems, which must work together to offer new services and open new market channels. Indeed, the focus is shifting from the internet of things (ioT)  and the internet of everything (IoE) to services and smart applications of the internet of systems. This last represents the required information technology need to make smart solutions to work correctly,  such as processes related to data collections, artificial intelligence, domotics, public services, critical infrastructures or national security ones. In fact the digital transformation is affecting everyday life aspect from defence, industry, healthcare, to smart cities and and smart home. It follows the main question we should think about is if we are doing enough the ensure about the security of these systems, in order to assure about the safety of the technology we are using.